Despite the backlash among the assembly, Mayor Pierce believes “this is a his poll is excellent and has been very well received.” Mayor Pierce took to Facebook to post an online poll for members of the Borough to weigh in on the proposed budget, but some members of the assembly have voiced their apprehension to how accurate the poll might be. KPB Mayor Pierce and his administration presented the FY2019 budget to the borough assembly at their meeting on May 15. According to a post on social media, Mayor Pierce feels like his “plan was initially shot down, and feels it is critical to listen to the people that he was elected to serve.” Facebook0TwitterEmailPrintFriendly分享Budget talks are looming all over the Kenai Peninsula, and Borough Mayor Charlie Pierce has taken to social media in an attempt to hear from the local residents regarding his recent FY2019 budget proposal. Assemblyman Willy Dunne: “It is difficult to fully understand all of the fiscal and economic implications of the choices presented in this simplistic and biased poll.” Of the nearly 400 borough residents that have taken the time to fill out the poll, the results are pretty evenly split, with the property tax option getting the least support. Assemblywoman Kelly Cooper commented: “This poll isn’t very clear so results will be skewed. This is messaging & not fair to our constituents. They’re savvy & will understand it. As presented, it’s simply a poll weighted to get the results you want.” A vote on the finalized budget for the FY2019 will go before the assembly on June 5.
The foster parents allowed the children to leave with the female. Later shown a photo of the person the woman claimed to be, the foster parents confirmed it was not the same female who took the children. Additional details will be posted as they are made available. ORIGINAL POSTThe Alaska State Troopers are searching for three children that were last seen in Seward on August 5. The children are identified as Slate Erickson, age 4; Jedidiah “Fox” Erickson, age 7; and Pepper Erickson, age 9.The investigation into the children’s disappearance revealed on August 5 a female arrived at the foster home claiming to be sent by OCS. The woman provided a name that the foster parents recognized as someone who they anticipated may be taking the children, but whom they had never met. Facebook0TwitterEmailPrintFriendly分享Last updated on August 12th, 2019 at 06:12 amUPDATE 3:40pmErickson children and mother Melissa Salgado have been found safe in Cordova. On August 6, the Office of Children’s Services requested Alaska State Troopers perform a welfare check for three children in foster care. The following day it was determined the children were wrongfully removed from a foster home in the Seward area by an unknown female. Further investigation has revealed the children’s mother, Melissa Salgado, 40, of Seward, is also missing. There is a concern the children could be anywhere along the road system.Anyone with information regarding the location of Salgado or the children is asked to contact the Alaska State Troopers in Soldotna at 907-262-4453.
ADC AUTHOR President Trump does not want a deal to raise mandatory spending caps, Axios reported Monday.The White House appears to be dug in on the topline numbers in the administration’s fiscal year 2020 budget request. The request pushes defense spending to $750 billion by putting extra money in the overseas contingency operations (OCO) account, which is not subject to spending caps.House Democrats and Senate Republicans have hoped to reach a deal to raise the limit on defense and nondefense spending, but the president “really wants to stick to his numbers and doesn’t want a caps deal, because that means more domestic spending,” a source told Axios.House Majority Leader Steny Hoyer (D-Md.) last week blamed Mick Mulvaney, the White House acting chief of staff and director of the Office of Management and Budget, for derailing bipartisan talks “to use it as leverage,” Hoyer said, as On Base reported.The House Budget Committee will consider legislation to raise the caps at a Wednesday meeting.Air Force photo by Staff Sgt. Westin Warburton
Hina Khan at Cannes Film Festival 2019ReutersTelevision actress Hina Khan dazzled like a diamond as she made her debut at Cannes Film Festival 2019 on Wednesday, May 15. Donning a grey shimmery gown with a plunging neckline and a gathered train, Hina walked the red carpet wearing a bright smiled and waving at the photographers.The actor is at Cannes for the screening of her short film, Lines, which is based on the Kargil War. She attended the screening of sci-fi drama Bacurau on Wednesday.The gorgeous actress, who made her TV debut with Yeh Rishta Kya Kehlata Hai, picked out her favourite moment from her Cannes debut and posted it on her social media page with a caption that read: “The picture is just not “a” picture.”As soon as Hina made her Cannes debut, Twitter burst out in praise. A user wrote, “HINA KHAN slayed omg wow” while another user said, “Okay so i could just get these Glimpses of #HinaKhan for you exclusively at #Cannes2019 She was looking like a Diva.” Just like every year, Aishwarya Rai Bachchan, Sonam Kapoor and Deepika Padukone will also attend the Cannes Film Festival 2019.On Sunday, Hina shot for her last episode of the popular TV show Kasautii Zindagii Kay 2 where she played the role of Komolika. Her co-stars including Erica Fernandes, Parth Samthaan, Pooja Banerjee among others had organised a mini farewell on the sets and wished her luck for future ventures. A few of the clicks were shared on Instagram. Before the big Cannes event, Hina also shot for an upcoming video song by Arijit Singh in Delhi. She is paired alongside her best friend and actor Priyank Sharma in the video.
Employees walk in a lobby at the Bombay Stock Exchange (BSE) during the announcement of the annual budget in Mumbai February 28, 2013 (representational image).Reuters fileRetail inflation data for June released the previous day lifted sentiments on Indian stock markets, with the benchmark indices Sensex and Nifty hitting new highs on Thursday in early trade. The Sensex crossed 32,000 while the 50-scrip Nifty was trading 65 points higher at 9,881.Top Sensex gainers were ITC, ICICI Bank and Axis Bank while stocks that were lifting the Nifty included ICICI Bank, ITC, Yes Bank and Indiabulls Housing Finance.Retail inflation hit a new low of 1.54 percent for June, buoying hopes of a rate cut by the Reserve Bank of India (RBI) when it meets for its next monetary policy meeting. Though the data was accompanied in the form of weak factory output at 1.7 percent for May from 2.8 percent (revised) for April, according to Moneycontrol.com, it did not impact the bull run.BusinessLine said in an analysis on Thursday that in the context of retail inflation falling to 1.54 percent, the “clamour for rate cuts has only gotten stronger.” Retail inflation dropped to a level not seen in many years, the ETEnergyworld said, citing chief economic advisor Arvind Subramanian. “The last time we saw such inflation — according to slightly different CPI (IW) — was in 1999 and before that in August 1978,” he said. In other news, TCS will be starting the Q1 results season by declaring its financial performance on Thursday, followed by Infosys the next day.Staying with stock markets, Bloomberg said in a report that the party could be spoiled by the uncertainty prompted by the implementation of the goods and services tax (GST) from July 1. “We don’t expect a great quarter looking at the impact of GST,” the news agency quoted A K Prabhakar, head of research at IDBI Capital Market Services Ltd., as saying.Citi analysts Surendra Goyal and Vijit Jain foresee a 2.4 percent drop in profit for Sensex companies. Investors should be cautious of volatility in view of the quarterly results for quite some time, according to Deutsche Bank AG analysts. “We are entering a phase of no like-for-like results for the next six quarters. As a result, they “expect heightened volatility and hawk-like focus on management commentary,” Bloomberg quoted Manoj Menon and Mihir P. Shah as writing in a note to clients.
Listen Jefferson said that another student heard about the plan and called in an anonymous tip to Crime Stoppers. The public safety nonprofit increasingly deals with school safety.Jefferson won’t reveal the school’s name to keep the tip line anonymous, and she won’t identify the student because he’s a minor. There’s also often a stigma attached to schools if they’re linked to threats or acts of violence.What she wanted to emphasize, though, is they took this tip very seriously. “There was a campus officer that was immediately contacted by one of our Crime Stoppers investigators and the juvenile who was identified was actually arrested for third degree felony and for terroristic threat,” Jefferson said. “And they were charged.”Jefferson said that later the school police didn’t find explosives on campus.Still, experts say this shooting that almost happened offers key lessons. “We’ve known that fellow students are an absolute critical part of prevention efforts,” said Marisa Randazzo. She used to work with the U.S. Secret Service as its chief research psychologist. Now she’s co-founded a company, SIGMA Threat Management, that’s helping Texas schools do threat assessments.Randazzo said that in over three quarters of actual school shootings, the shooter told someone about his plans. So, authorities need to hear from that someone: “When we can encourage people to come forward and let people know if they hear about something, like in this case, if someone is talking about planning to engage in violence at school, it is quite possible to prevent, just like it has been done here.”In fact, the National Police Foundation has started a database, where schools and districts can volunteer information about these shootings that were averted. It’s trying to study these cases so other schools can protect students and staff. Some early lessons include:Schools and law enforcement need strong relationships and open communication before an attack occurs;In over half the cases in the database, students were the first to discover another student’s plan. So, students should be encouraged to report threats and also coached on how to recognize signs of self-harm and depression;Threats should be taken seriously; andParents should monitor social media accounts and what their children are searching online.In the local case from 2017, Crime Stoppers had visited the Houston-area high school months before the threat. They coached over 2,000 teenagers on how to report tips in two sessions at the start of that school year.“What went right is that the student that reported anonymously had been trained and knew what to do,” said Rania Mankarious, Crime Stoppers’ CEO.Laura IsenseeRania Mankarious leads Crime Stoppers of Houston.But, Mankarious said, it was still a close call. “What went wrong is the boy who made the threat had been operating under the radar until we came in and educated people,” she said. “Nobody knew what to look for. Nobody noticed that his language and activity had changed. So that’s a problem.”Crime Stoppers, along with other state and national groups, are trying to reach more schools with lessons on “what to look for” — so would-be shooters are stopped before they can act. Via The Texas Tribune Police tape in front of Santa Fe High School in Santa Fe, Texas on May 20, 2018.It can be the most dreaded news a parent can hear: a shooting at their child’s school.It happened six years ago at Sandy Hook Elementary. Then this February in Parkland, Florida. And then just outside of Houston in May, when 10 people were killed and 13 others injured when a gunman opened fire at Santa Fe High School.But as horrific as that list is, it would be even longer if it included school shootings that almost happened.News 88.7 found one such case in Greater Houston, when a ninth grader at a local high school made a threat in February, 2017.“He pretty much told his plans of placing bombs in a school cafeteria,” said Lt. Tiffany Jefferson, a Houston police officer who works with Crime Stoppers of Houston. “And that student went on to say that when the bombs explode and the students are going to flee the building, they will be shot.” To embed this piece of audio in your site, please use this code: 00:00 /03:54 Share X
Courtesy of Dr. Jessica Fitzsimmons/Texas A&M GeosciencesThe Houston Shipping Channel near Alexander Island. Texas A&M researchers say they’ve spotted abnormal water conditions near last week’s Deer Park chemical disaster. The team has been collecting water and air quality samples in Galveston Bay quarterly since June 2017. They won’t have lab results from their March 23 samples for another two weeks, but Dr. Jessica Fitzsimmons said the residue suggests chemical compounds, likely from the ITC runoff. “When we put our hands in the water and our hands came up and dried, it wasn’t a feeling that you normally get when sea water dries on your hands,” she said. “Instead we had a waxy feeling on our hands that was an indicator that there is something different in the waters, even in greater Galveston Bay — in the northwest corner of greater Galveston Bay.”According to the Texas Commission on Environmental Quality, their water sampling hasn’t found any cause for concern. “I think my surprise came from the fact that we didn’t expect this to have come quite as far south as it did, if we can assume what we saw came from Deer Park, which is our current assumption,” Fitzsimmons said.Intercontinental Terminals Company said sensitive marsh areas near their facility haven’t been impacted.ITC clean-up continuesITC said in a news release that, as of Wednesday morning, responders had removed approximately 696,990 gallons of oily water from the waterways impacted by the incident, which includes the Houston Ship Channel and several regional bayous such as Buffalo and Tucker.In addition, approximately 1.5 million gallons of product mixed with water and firefighting foam had been removed.Response personnel are still foaming the tank farm as needed to maintain at least a 2-foot level of foam, by pumping a mix of firefighting foam, water and remaining product from the ditch using vacuum trucks and hoses.ITC executive Brent Weber said at a news conference Thursday the focus was to finish emptying tanks that contain gasoline blend stocks and base oil. Naphtha, which is highly flammable, is the base component in the gas blend stock. He also noted that all the Pygas had been transferred out of the tank farm.“Progress continues to be steady,” said Weber, while adding his company is also repairing ditches and assisting the EPA and the U.S. Coast Guard with cleaning the waterways.Both Harris County and ITC said in news releases that there are currently no known or suspected impacts to drinking water.The Texas Department of State Health Services has updated its fish consumption advisory for the upper Houston Ship Channel and recommends not eating any fish or crab from the ship channel or San Jacinto River north of the State Highway 146 Fred Hartman Bridge.The Houston Ship Channel is currently open to traffic between Tucker Bayou and HSC Light 116 through coordinated vessel movement by the Coast Guard.The San Jacinto River also remains open for vessel traffic during daylight hours only, and there are specific sites set up to observe transiting vessels that may require decontamination. Coast Guard Captain Kevin Oditt said at the news conference he didn’t have a timeframe on full reopening of the Channel.ITC also posted a video statement from CEO Bernt Netland on YouTube in which he addresses the incident and apologizes. 00:00 /00:49 To embed this piece of audio in your site, please use this code: Share X Listen
Kolkata: Maulana Abul Kalam Azad University of Technology (MAKAUT) is coming up with its third campus in Darjeeling with a focus on employable courses.The state Higher Education department has already written to the District Magistrate of Darjeeling for earmarking a 7 acre land in the Hills in which MAKAUT, formerly known as West Bengal University of Technology, plans to set up its new campus. “We have already made a detailed planning of what we actually want to do in the new campus and have submitted a proposal to the Higher Education department. We will be introducing courses based on the employability in the Hills so that students get jobs after completion of the courses,” Saikat Maitra, Vice-Chancellor of MAKAUT, said. Also Read – Rain batters Kolkata, cripples normal lifePresently, Makaut has two campuses — one at Salt Lake and another at Haringhata in Nadia district. The technology university presently has around 90 engineering colleges and 110 professional colleges across the state affiliated to it. A senior academic official of the university said courses on media science, hospitality management, travel and tourism with focus on the tea industry, food processing and its packaging are on the radar. “Landslides are quite common in the Hills and so courses on disaster management are also in our plan,” the official added. Also Read – Speeding Jaguar crashes into Mercedes car in Kolkata, 2 pedestrians killedThe proposed new campus will have facilities for small business clusters, training facilities and state-of-the-art infrastructural facilities. “The scenic beauty of the Hills has always encouraged filmmakers from both Hollywood and Tollywood. So, Darjeeling has enormous potential to be developed as a film hub. If we can churn in professionals of media science, the idea can well be a reality,” the official maintained. “We are constantly upgrading our existing curriculum according to the demands of the industry to ensure employability for the students. All India Council of Technical Education (AICTE) has urged all universities across the country to frame its curriculum in a manner so that it keeps pace with the changing times and we are leaving no stones unturned. More than 20 new courses have been introduced from this academic year,” Maitra said. The new professional courses have been designed in consultation with the Chambers of Commerce based nationally as well as at the state level.
Kolkata: Eight lakh people have visited Mother’s Wax Museum since its inception in November 2014. With a member of a family from Meghalaya, who visited the museum on Monday, the number of visitors exceeded 8 lakh.Named after Mother Teresa, the museum was inaugurated by Chief Minister Mamata Banerjee from the dais of Kolkata International Film Festival on November 10, 2014. The souvenir shop in particular is very popular from where people can buy exclusive souvenir and memories. Various types of Also Read – Bose & Gandhi: More similar than apart, says Sugata Boset-shirts and caps are also sold in the shop. The museum is divided into several sections, which include wax statues of famous people from the world of entertainment, noted scientists, novelists, personalities and cricketers. “The sports section is the most popular, where one can get to see the statues of great cricket personalities such as Kapil Dev, Sachin Tendulkar and Sourav Ganguly and present Indian skipper Virat Kohli,” an official from the West Bengal Housing and Infrastructure Development Corporation (HIDCO) said. Also Read – Rs 13,000 crore investment to provide 2 lakh jobs: MamataThe fantasy section, which includes statues of Chota Bheem, Doraemon and Spider Man, has become very popular among the children. Selfies with the wax figurines at the museum has been a trend among the visitors. A visitor also can get his/her own 3D selfie at the museum. HIDCO has recently introduced this cutting-edge technology through which a person’s face/head is scanned 360 degrees and a golf ball sized (slightly smaller) 3D sculpture is printed by a 3D printer. The finished sculpture is couriered in 48 hours, of course at a cost. The finished sculpture comes at a price of Rs 2,000 (including courier charges). The process is done adjacent to the souvenir counter at the museum and a person only has to sit in a chair for the 3D selfie. The use of technology for 3D selfies is emerging as a fun element and the response from the visitors have been quite good. HIDCO chairman Debashis Sen said. An agency had approached HIDCO with this concept and it has been accepted.
Learn how to successfully navigate family business dynamics and build businesses that excel. March 14, 2017 Tom Brant Next Article –shares Google Add to Queue A $350 pair of Levi’s that syncs with your smartphone? Is it Fashion Week again? No, it’s South by Southwest, the annual gathering of tech enthusiasts and culture lovers, where Google and Levi’s offered an update on a project they’ve been working on to make a stylish denim garment full of technology.The garment isn’t jeans, though, it’s a special version of Levi’s Trucker jacket woven out of electronic threads that Google is working on as part of its Project Jacquard. First announced in 2015, the jacket is inching closer to reality with a price tag and a release date of “this fall,” according to Engadget.For $350, you’ll get a jacket that takes the term “wearable” — traditionally used for smartwatches — to new heights. A small tag will be embedded in the denim, containing all the electronic components the jacket needs to connect to your smartphone. The rest of the garment looks like any other Trucker jacket, except you can swipe it to take calls and use other smartphone functions when your device isn’t easily accessible.The target audience is urban bike riders: a promotional video shows a biker swiping his sleeve to change song tracks, get navigation directions and answer calls. The electronic fibers woven into the denim capture touch interactions, and use machine-learning algorithms to determine various gestures. Data is then wirelessly transmitted via the electronic tag — removable for washing — to a mobile device.This being Google, of course, Project Jacquard isn’t stopping at a denim jacket for fashion-conscious techies who commute to work by bike. The company envisions the fabric being used by any fashion designer, and it is working on developing an ecosystem of apps and cloud services to convince people that the high-tech fabric is worth a higher price.Speaking of paying a premium, you can pick up a “dumb” Trucker jacket right now for $65. We’re betting some people will find it worth spending an extra $285 to answer phone calls from their coat sleeve, but many more won’t. Image credit: via PC Mag 2 min read News reporter This story originally appeared on PCMag Commute by Bike? Check Out Google’s $350 Smart Jacket. The Google-Levi’s partnership takes the term ‘wearable’ to new heights (and price tags). Free Webinar | July 31: Secrets to Running a Successful Family Business Register Now »
Attend this free webinar and learn how you can maximize efficiency while getting the most critical things done right. July 21, 2017 The new feature inside Amazon’s iPhone app lets you follow specific categories and people, making it easy to buy things you find. Add to Queue Image credit: Amazon via PCMag Amazon Amazon Spark Is a Pinterest-Like Shopping Social Network Next Article Angela Moscaritolo Free Webinar | Sept 5: Tips and Tools for Making Progress Toward Important Goals As if you don’t already buy enough stuff on Amazon, the ecommerce giant just added a new Pinterest-like feature to its iPhone app aimed at helping you “find more of what you like.”Dubbed Spark, the new shopping social network lets you follow specific categories and people. Of course, Amazon has made it super easy to buy things there, too.To access Spark, tap the hamburger icon (three parallel horizontal lines) in the Amazon iPhone app, select Programs and Features, then tap Spark. The first time you visit, you’ll select a few of your interests: things like books, style and fashion, food, technology, do it yourself (DIY), home décor, beauty, recipes, video games and women’s fashion, for instance.From there, Spark will create a “feed of personalized content from other Amazon customers with similar interests as you.” If you see something you like, just tap the product link or shopping bag icon to buy it.You can also create posts to share a specific product or story, and “interact with people by commenting or smiling on their posts.” We assume “smiling” on someone’s post is basically like adding a heart or thumbs up.Anyone in the U.S. with the Amazon iPhone app can look at posts on Spark, but you’ll need to be a paid Prime member to contribute your own.Just keep in mind that whatever you do on Spark is pretty much public. “Anyone can view your posts, comments, the interests you follow and see your Amazon Profile,” Amazon said in its Spark FAQs. Your profile displays customer reviews you’ve written but does not show your purchasing or browsing history. This story originally appeared on PCMag 2 min read –shares Reporter Register Now »
Admetrics, a marketing intelligence company that supports advertisers with data science solutions to gain actionable insights into their marketing data, announced the release of Newton, a new capability that enables companies to run always-on experimentation for insight generation at scale.Newton represents a shift in marketing intelligence software, providing marketers a simple way to turn any marketing data into countless experiments running in parallel to learn, optimize and iterate at scale by continuously analyzing data and making recommendations for growth. In this capacity, Newton functions as a 24/7 expert and advisor, drawing from deep domain expertise to convert data into knowledge, proactively identifying insights and actions to drive positive business outcomes.The ability of Newton to evaluate options and alternatives, determine cause-and-effect relationships and predict highly probable and profitable outcomes positions marketers to bridge the growing disconnect between information and insights. Research firm Forrester puts the scope of the problem into perspective, observing that a massive 60 to 73% of data companies collect is not analyzed.The outcome is a vicious cycle in which marketers invest massive resources to gather tremendous amounts of data from an ever-increasing number of sources and channels—and yet lack the capabilities to turn that information into action, according to a 2019 survey of CMOs and brand marketers reported in Inc. magazine. This also dovetails with Admetrics internal data that shows the majority of brands (57%) have “access to sufficient data resources,” but, at the same time, critically lack capabilities to address and execute data-informed tasks including testing, reporting and bidding model optimization.Marketing Technology News: Blis Expands Into the Netherlands With First HireNewton was architected to address this issue, providing marketers the capabilities to automate and scale data analysis in order to maximize insight generation and increase cost efficiency. To achieve this, Newton leverages Quantify, the Admetrics experimentation engine released in March, to provide highly accurate statistical results at the highest possible pace. This enables quicker time to value and dramatically faster data-driven decision making than traditional testing methodologies by empowering marketers and campaign managers to continuously learn from ever-running experiments.Leading data-driven companies across categories have developed their own experimentation platforms in order to outpace their competition. It’s a competitive advantage that used to demand significant investment and data science expertise, but this is changing with the advance of next-generation solutions, according to Markus Repetschnig, CEO and co-founder at Admetrics.“The release of Newton, which was purpose-built to supercharge experimentation and data analytics by suggesting actions marketers can take to optimize growth, marks a turning point in what all companies can achieve—even if they lack big budgets and large data science teams,” Repetschnig explains.Marketing Technology News: Shoppers Take Center Stage in the 2019 Retail Systems Research Report on eCommerce Website Performance“Newton helps advertisers and agencies minimize missed opportunities for growth and stop losses as early as possible,” Repetschnig says. More importantly, Newton is also one of the first in a new breed of augmented analytics solutions, a cutting-edge category of data capabilities Gartner has identified as a top 10 strategic tech trend for 2019. In practice, Newton harnesses AI models that are tailored to specific advertising value and attribution chains to generate insight and provide actionable recommendations at scale, while minimizing the human component previously required to find issues and opportunities hidden deep in the data.Advertisers and agencies that want to leverage the new capability do not need to change their existing infrastructure as Newton works with any kind of marketing data and can be easily plugged into any tech stack. To date, Newton offers expert models for programmatic advertising and social platforms like Facebook, with additional models in the pipeline to address other marketing use cases.Marketing Technology News: Mongolia’s Mongolsat Networks Optimizes Multi-Screen Video Delivery with Verimatrix and moTV.eu AdmetricsMarketing AImarketing intelligenceMarketing TechnologyMarkus RepetschnigNews Previous ArticleCardinal Path’s 2019 State of Marketing Technology Report Highlights Consolidation & DisruptionNext ArticleTableau Welcomes More than 2,000 Customers and Partners to Berlin for Sold-Out European Conference Admetrics Launches Marketing AI Assistant Newton to Advise Marketers on Growth Opportunities MTS Staff WriterJune 19, 2019, 10:40 pmJune 19, 2019
Source:http://www.neuromed.it/ Reviewed by James Ives, M.Psych. (Editor)Dec 12 2018While the heavy negative effects of high consumption are confirmed, those who drink in moderation resort less to the hospital than teetotalersA study of the Department of Epidemiology and Prevention of I.R.C.C.S. Neuromed (Pozzilli, Italy), in collaboration with the Department of Nutrition of the Harvard T.H. Chan School of Public Health (Boston), highlights that people who consume alcohol moderately (one glass of wine a day), in the general framework of Mediterranean diet principles, have a lower risk of being hospitalized compared to heavier drinkers, but also to the teetotallers.The research, published in the scientific journal Addiction, involved 21,000 participants in the Moli-sani epidemiological study, followed for over 6 years. During this period, their drinking habits were related to their number of hospital admissions.Related StoriesRecreational marijuana users tend to drink more alcohol, medicinal users drink lessExcess grey matter in the brain can predict escalating drinking behavior in teensPeople use executive control processes to ignore cues that signal something rewarding”We observed – says Simona Costanzo, first author of the paper, who spent a period of research in this field at Harvard University, thanks to a grant from the Veronesi Foundation – that a heavy consumption of alcohol is associated with a higher probability of hospitalization, especially for cancer and alcohol-related diseases. This confirms the harmful effect of excessive alcohol drinking on the health. On the other hand, those who drink in moderation present a lower risk of hospitalization for all causes and for cardiovascular diseases compared to lifetime abstainers and former drinkers “.”The data on hospitalizations – comments Licia Iacoviello, Head of the Laboratory of Molecular and Nutritional Epidemiology of I.R.C.C.S. Neuromed and professor of Hygiene and Public Health at the University of Insubria in Varese – is very important in relation to the impact of alcohol on public health. Hospital admissions, in fact, represent not only a serious problem for people, but they have also a strong impact on National health systems. Our study confirms how much excess alcohol can weigh on healthcare facilities, underlining the urgent need of managing the problem, but it also confirms and extends our previous observations according to which moderate alcohol consumption is associated with a reduction in mortality risk, regardless of the type of disease”.”We are absolutely not saying – underlines Ken Mukamal Associate Professor of Medicine at Harvard Medical School – that any teetotaler should start drinking to improve his/her health. However, this research reaffirms that the effects of alcohol consumption cannot be reduced to a single catchphrase or punchline. This very comprehensive study clearly shows that we need to consider its health effects based upon both dose and disease”.
Reviewed by Alina Shrourou, B.Sc. (Editor)Dec 20 2018Scientists have taken a key step toward improving an emerging class of treatments for Parkinson’s disease.The advance could markedly improve a next generation of therapies for the condition, which affects around one in 350 people in the UK.It could aid development of the promising treatment – known as cell replacement therapy – which was first used in a clinical trial this year. Experts hope the approach, which involves transplanting healthy cells into parts of the brain damaged by Parkinson’s, could alleviate symptoms such as tremor and balance problems.The latest development addresses limitations in the treatment in which, over time, transplanted tissue can acquire signs of disease from nearby cells.Related StoriesExciting study shows how centrioles center the process of cell divisionStudy: Megakaryocytes play an important role in cell migrationNanoparticles used to deliver CRISPR gene editing tools into the cellResearchers at the University of Edinburgh have created stem cells – which have the ability to transform into any cell type – that are resistant to developing Parkinson’s.They snipped out sections of DNA from human cells in the lab using advanced technology known as CRISPR. In doing so, they removed a gene linked to the formation of toxic clumps, known as Lewy bodies, which are typical of Parkinson’s brain cells.In lab tests, the stem cells were transformed into brain cells that produce dopamine – a key brain chemical that is lost in Parkinson’s – in a dish. The cells were then treated with a chemical agent to induce Lewy bodies.Cells that had been gene-edited did not form the toxic clumps, compared with unedited cells, which developed signs of Parkinson’s.Researchers say the advance could be most beneficial to younger patients living with Parkinson’s and those with an aggressive form of the condition, but that the advance had to be tested in human trials.The study, published in the European Journal of Neuroscience, was funded by the UK Centre for Mammalian Synthetic Biology, the pharmaceutical company UCB Biopharma and The Cure Parkinson’s Trust.Dr Tilo Kunath of the Medical Research Council’s Centre for Regenerative Medicine at the University of Edinburgh, who led the study, said: “We know that Parkinson’s disease spreads from neuron-neuron, invading healthy cells. This could essentially put a shelf life on the potential of cell replacement therapy. Our exciting discovery has the potential to considerably improve these emerging treatments.”Dr Simon Stott, Deputy Director of Research for the Cure Parkinson’s Trust said, “Cell replacement therapy represents one experimental approach to regenerative medicine for people with Parkinson’s. This new research by Dr Tilo Kunath and his team at the University of Edinburgh provides another advancement in the development of this treatment. The Cure Parkinson’s Trust is thrilled to be associated with this inspiring and innovative research” Source:https://www.ed.ac.uk/news/2018/stem-cell-approach-could-aid-parkinson-s-fight
Reviewed by Alina Shrourou, B.Sc. (Editor)Jan 3 2019Psychiatric disorders share common alterations of functional connectivity between three core brain networks involved in cognition, according to a meta-analysis published in Biological Psychiatry. The network alterations were localized in brain regions underlying general cognitive performance. The study suggests that the alterations in these networks contribute to the cognitive dysfunction present in multiple psychiatric disorders.The alterations in functional connectivity, which emerged from a meta-analysis of 242 functional brain imaging studies in people with a variety of psychiatric disorders, were found in the three large-scale networks considered to be particularly important for complex cognition–the default mode network; frontoparietal network; and the salience network. Further, analysis of 363 structural brain imaging studies revealed reduced gray matter that was confined to the altered networks, tightly linking structural and functional alterations.Related StoriesIT Faces the Digital Pathology Data TsunamiResearch team to create new technology for tackling concussionNANOLIVE‘s novel CX-A defines a new standard for live cell imaging in 96 well plates for continuous organelle monitoring in cell populationsImportantly, the study provides the first evidence from a meta-analysis of common functional connectivity alterations in neurocognitive networks across psychiatric disorders. “This new knowledge calls for studying brain-based diagnostic biomarkers of psychiatric disorders that are beyond traditional diagnostic boundaries,” said senior author Yong He, PhD, Beijing Normal University, China.Although psychiatric illnesses are considered to be distinct disorders, cognitive dysfunction appears in most of them. This overlap of symptoms across psychiatric disorders has been a major challenge to precisely categorize patients. Although enormous progress has been made in characterizing the neural correlates of diagnoses and symptoms over the past 25 years, neuroimaging biomarkers have yet to contribute to the psychiatric diagnostic process.”Dr. He and colleagues provide an important clue as to why neuroimaging diagnostic biomarkers have made limited progress,” said John Krystal, MD, Editor of Biological Psychiatry. “This finding pushes us to rethink the potential role of neuroimaging in the diagnostic process.”The shared neurocognitive network alterations suggest that neuroimaging may be providing a measure of symptom-related pathology not directly related to the disease process. This could pose a problem, as the study of psychiatric disorders–which are defined by collections of symptoms–is primarily limited to the study of behaviors. It is possible that disease-specific elements of biology exist, but the similarity between disorders in this study indicate that greater efforts may be needed to adjust for common elements of pathology in the search for “disease-specific” biomarkers. Source:http://www.elsevier.com/
Moving toward independenceRoger Kay, founder and analyst at Endpoint Technologies Associates, said the ban is likely to accelerate efforts by Huawei and other Chinese firms to develop their own sources of microprocessors and other components.”The short-term effect on both American and Chinese companies are inevitably negative,” Kay said.”The longer-term effect is that Huawei and other Chinese companies turn away more sharply from American suppliers.”Neither Intel nor Qualcomm responded to queries on how they would respond to the order on Huawei.Avi Greengart, founder of the research firm Techsponential, said a ban on sales to Huawei could hit a wide range of large and small US firms including Corning, which makes the popular Gorilla Glass for smartphones, and Dolby, a producer of video and audio software for handsets. The tough sanctions imposed on Huawei by President Donald Trump could deal a blow to the many US firms that make up the Chinese tech giant’s supply chain. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Explore further American firms last year sold an estimated $11 billion worth of components to Huawei, which was put on a blacklist last week by Washington over national security concerns as trade frictions grow between the US and China.Trump’s executive order could effectively ban makers of US hardware and software from selling to Huawei by requiring a special license from Washington.Bloomberg News reported that US-based chipmakers Intel, Qualcomm, Broadcom and Xilinx have indicated they would halt shipments to the Chinese firm which is the world’s number two smartphone maker and a leader in telecom infrastructure and super-fast 5G networks.Google said it would comply with the US order, leaving Huawei without access to critical services for the Android operating system such as Gmail and Google Maps.Microsoft, which supplies the Windows operating system for many Huawei devices, did not respond to an AFP query on how the order might impact the Redmond, Washington-based firm.Bob O’Donnell of the consultancy Technalysis Research said any ban would almost certainly affect Microsoft.”If it affects Google I don’t see why it wouldn’t affect Microsoft,” O’Donnell said.”Any version of Windows comes from Microsoft, since there is no open-source version.” Citation: US tech firms to take hit from Huawei sanctions (2019, May 20) retrieved 17 July 2019 from https://phys.org/news/2019-05-tech-firms-huawei-sanctions.html Apple could suffer from a backlash in China if the crisis over Huawei persists, according to analysts © 2019 AFP Google v Huawei hits millions of smartphone users The sanctions on Huawei are likely to impact US firms selling billions of dollars of components to the Chinese tech giant Risks to AppleGreengart said Apple could also suffer from any protracted crisis over Huawei, estimating the iPhone maker gets about 17 percent of its revenues from China.Even though Apple might benefit in the premium smartphone market in Europe, “I think the risks are higher than the rewards for Apple,” Greengart said.”If there is a backlash against Apple in China, that could have damaging long-term effects.”Greengart said that Google might not see a major impact for the moment.”Ironically (the ban) won’t affect Google much because Google doesn’t make money selling Android.”Patrick Moorhead, of Moor Insights & Strategy, said he sees a limited impact on US firms in the short run.”The impact to the US companies depends on the length of the ban but also how indexed they are in sales to Huawei,” Moorhead said.”Neither Intel, Google or Nvidia do more than three percent of their business with Huawei, so short-term, it shouldn’t be an issue.”O’Donnell said a bigger risk is that Huawei and other Chinese firms step up efforts to develop software and hardware that allows them to break free from Silicon Valley.”The longer-term question is: does this drive Huawei to develop a third mobile platform?” O’Donnell said.”China is already developing its own technology infrastructure, and this plays into the whole notion of a separate internet in China, which would be a big deal.” Chipmakers Qualcomm and Intel are among the suppliers to Huawei which could be affected by the US ban on sales to the Chinese firm “When you think about all the software and hardware components you get a pretty big list,” Greengart said.”The US is a big part of the global supply chain.”Few firms offered public comments on their response to the Huawei executive order.But one, California-based Lumentum Holdings, a maker of optical and laser applications, said it would comply with the executive order and that Huawei accounted for 15 percent of its revenue so far in the current fiscal year.
U.S. suppliers are taking a hit, too. Micron Technologies, Qualcomm, Qorvo and Skyworks Solutions have all listed Huawei as a major customer. Last week, chipmaker Broadcom reduced its 2019 revenue forecast by $2 billion, saying customers are trimming orders because of the trade tensions, including the U.S. curbs on sales to Huawei. Broadcom previously estimated full-year revenue of $24.5 billion. The research firm IHS Markit said Micron and Western Digital will also suffer, as they lose a leading buyer of memory chips and storage devices.Huawei is expected to face challenges finding alternative suppliers for components, though IHS says Micron and Western Digital could eventually be replaced by South Korean and Taiwanese suppliers.More broadly, U.S. businesses are expressing alarm at the Trump administration’s aggressive policies toward China. Hundreds of companies, trade groups and individuals have written the U.S. trade representative to protest the administration’s plan to extend tariffs of up to 25% on the $300 billion worth of Chinese sales to the United States that haven’t already been hit by import taxes. Huawei founder Ren Zhengfei, center, speaks at a roundtable at the telecom giant’s headquarters in Shenzhen in southern China on Monday, June 17, 2019. Huawei’s founder has likened his company to a badly damaged plane and says revenues will be $30 billion less than forecast over the next two years. (AP Photo/Dake Kang) Huawei founder Ren Zhengfei speaks at a roundtable at the telecom giant’s headquarters in Shenzhen in southern China on Monday, June 17, 2019. Huawei’s founder has likened his company to a badly damaged plane and says revenues will be $30 billion less than forecast over the next two years. (AP Photo/Dake Kang) © 2019 The Associated Press. All rights reserved. Huawei founder Ren Zhengfei speaks at a roundtable at the telecom giant’s headquarters in Shenzhen in southern China on Monday, June 17, 2019. Huawei’s founder has likened his company to a badly damaged plane and says revenues will be $30 billion less than forecast over the next two years. (AP Photo/Dake Kang) Huawei founder Ren Zhengfei, left, gets make up on his face before attending a roundtable at the telecom giant’s headquarters in Shenzhen in southern China on Monday, June 17, 2019. Huawei’s founder has likened his company to a badly damaged plane and says revenues will be $30 billion less than forecast over the next two years. (AP Photo/Dake Kang) Huawei’s founder said Monday that the Chinese telecom giant’s revenue will be $30 billion less than forecast over the next two years, as he compared the company to a “badly damaged plane” as a result of U.S. government actions against it. China telecom giant Huawei hints US pressure hurting sales Ren denies that Huawei would share user data with the Chinese government if ordered to do so. He said Monday there are no backdoors in its equipment that anyone could access, and that Huawei is willing to enter into a no backdoor agreement with any nation that wants one.Huawei has brought a lawsuit in the U.S. this March challenging the constitutionality of a national security law which prevents the U.S. government and its contractors from using Huawei equipment. The complaint, filed in Plano, Texas, where Huawei’s American operations are headquartered, alleges that the law singles out Huawei for punishment while denying the company due process.The Wall Street Journal reported last week that Huawei is asking Verizon to pay licensing fees for more than 200 of its patents. While Huawei declined to comment on the matter, company spokesman Joe Kelly said it will hold a briefing later this month on being more aggressive about collecting intellectual property licensing fees.Ren said during the panel discussion that Huawei will not use its many patents as a “weapon,” but did not rule out seeking royalties for usage.He emphasized that Huawei will not stop collaborating with other countries and businesses. Explore further Citation: Huawei says US sanctions will cost it billions in revenue (2019, June 17) retrieved 17 July 2019 from https://phys.org/news/2019-06-huawei-founder-revenue-billions.html This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. The company’s current situation “is not caused by American businesses, but rather by certain politicians’ different perspectives,” Ren said. “I think both sides will suffer. No one will win.”The panel, organized by Huawei, also included Nicholas Negroponte, the founder of the media lab at the Massachusetts Institute of Technology, and writer and investor George Gilder.In December, Huawei Chief Financial Officer Meng Wanzhou—Ren’s daughter—was arrested in Vancouver at the request of U.S. authorities. The U.S. alleges that Meng misled American banks about the company’s business dealings with Iran, and that Huawei used a Hong Kong shell company to sell equipment in Iran in violation of U.S. sanctions. An extradition hearing is expected to begin in January. Some are showing up in person for seven days of hearings that begin Monday. They want the administration to cancel the tariffs—or at least spare the imports they rely on.Washington claims Huawei poses a national security threat because it is beholden to China’s ruling Communist Party. But American officials have presented no evidence of any Huawei equipment serving as intentional conduits for espionage by Beijing. Huawei’s placement on the Entity List is widely seen as intended to persuade resistant U.S. allies in Europe to exclude Huawei equipment from their next-generation wireless networks, known as 5G. “We never thought that the U.S.’s determination to attack Huawei would be so strong, so firm,” Ren Zhengfei, who is also the CEO, said during a panel discussion at the company’s headquarters in Shenzhen, China.Ren said Huawei will reduce capacity and expects revenue of about $100 billion annually for the next two years, compared with $105 billion in 2018. In February, he said the company was targeting $125 billion in 2019.Huawei’s overseas cellphone sales will drop by 40%, Ren said, confirming a Bloomberg report published Sunday. But the Chinese market is growing rapidly, he said, and Huawei will not allow restrictive measures to curb its research and development.Huawei is embroiled in a trade dispute between China and the U.S., which has accused Chinese companies such as Huawei of committing forced technology transfers and stealing trade secrets. Last month, the U.S. placed Huawei on its “Entity List,” which effectively bars American companies from selling components to Huawei without government approval.